Serveur d'exploration sur le lymphœdème

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CLEC-2 is required for development and maintenance of lymph nodes

Identifieur interne : 002C87 ( Main/Exploration ); précédent : 002C86; suivant : 002C88

CLEC-2 is required for development and maintenance of lymph nodes

Auteurs : Cécile Bénézech ; Saba Nayar ; Brenda A. Finney [Royaume-Uni] ; David R. Withers ; Kate Lowe [Royaume-Uni] ; Guillaume E. Desanti ; Clare L. Marriott ; Steve P. Watson [Royaume-Uni] ; Jorge H. Caama O ; Christopher D. Buckley ; Francesca Barone

Source :

RBID : PMC:4023425

Abstract

Key Points

CLEC-2 is necessary for lymphatic cell proliferation and lymph node anlage persistence after birth.

Lack of CLEC-2 expression on megakaryocytes and platelets compromises lymph node integrity in adult life.


Url:
DOI: 10.1182/blood-2013-03-489286
PubMed: 24532804
PubMed Central: 4023425


Affiliations:


Links toward previous steps (curation, corpus...)


Le document en format XML

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<p>Lack of CLEC-2 expression on megakaryocytes and platelets compromises lymph node integrity in adult life.</p>
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